Main The Testosterone Optimization Therapy Bible: The Ultimate Guide to Living a Fully Optimized Life

The Testosterone Optimization Therapy Bible: The Ultimate Guide to Living a Fully Optimized Life

Are you aware of the worldwide crisis thats robbing men of their masculinity, their sex drive, and their enthusiasm for life as a whole?

This is not scaremongering, nor is it a conspiracy theory - its the cold hard truth. Its well-established that testosterone levels decrease by 1% a year after the age of 30, and up to 40% of grown adult men are dealing with low testosterone levels. And this is further compounded by all the pollution in our environment that messes up our hormones.

The TOT Bible is jam-packed with cutting-edge, evidence-based information that incorporates the latest medical advancements and experience-based knowledge of the top progressive physicians, and is the ONLY reference for optimizing testosterone levels and male hormonal health!
This book will teach you:

—Why optimizing your testosterone is essential for helping your body function properly, and how it affects far more than your muscles or your physical strength.
—How optimized levels of testosterone can help you reclaim your health, vitality, and masculinity.
—Why obesity is so common in men with suboptimal levels of testosterone and how you can reduce body fat permanently.
—The SHOCKING TRUTH about the nearly unavoidable lifestyle, health and environmental factors that negatively affect your testosterone levels.
— High-performance nutrition, training, and body-mind-spirit strategies to take your life to the next level.
— The best treatment options that are currently available for the safe and productive use of therapeutic testosterone.
— A complete scientific demolition of the mainstream myths and misconceptions surrounding the usage and demonization of therapeutic testosterone.
— A painstakingly compiled list of game-changing supplements and medications - found nowhere else - that will completely alter your physique and enhance your mental performance.
— Womens Hormonal Optimization Therapy (HOT) as practiced by a leading physician and a high achieving mother with five children - a hormonally balanced partner means a better relationship for you.

If youre an average guy with average ambitions, then this book is not for you. This book is for men who want to become the BEST possible version of themselves and live an incredible life of optimal health and vitality.
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Copyright © 2018 Jay Campbell & Jim Brown

All rights reserved. No part of this book may be used or reproduced in any manner whatsoever without prior written consent of the authors, except as provided by the United States of America copyright law.

Published by Best Seller Publishing®, Pasadena, CA

Best Seller Publishing® is a registered trademark

Printed in the United States of America.

ISBN 978-1-946978-53-0

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Praise for The TOT Bible

I doubt there is a single disease, disorder, or deficiency that doctors haven't managed to confuse, complicate, and coerce into conforming to their belief that "their way is the best way." Nowhere is this hubris more apparent and problematic than in hormone optimization therapy. With Jay and Jim’s The TOT Bible, order has been brought to the chaos and clarity to the confusion. Based on years of experience, tens of thousands of hours of research, and hundreds of interviews with the top thought leaders in TOT, Jay and Jim have successfully synthesized the true best practices;  into a clear and concise resource that should occupy every man's (patient and physician’s) library.

Jim Meehan, MD

Chief Medical Officer, BodMD, PC

Every now and then a book is published that literally can and will change the trajectory of your life. The TOT Bible: The Ultimate Guide to Living a Fully Optimized Life is a must read for the physician and the patient. The field of interventional endocrinology has advanced dramatically in the past decade, exposing the numerous subtleties required for expert hormone replacement therapy. Jay and Jim have interviewed and assembled powerful insights into this field of endeavor, giving you, the reader, their years of expertise and authoritarian information that brings you to the pinnacle of TOT. Insights from numerous thought leaders with decades of clinical experience will educate, inform and enlighten. Welcome to the “Tip of the Spear”!

Rob Kominiarek, D.O., FACOFP

Founder ReNue Health

Jay Campbell’s The TOT Bible serves as both a primer and a DEEP DIVE that supersedes much of the academic writing out there. Our practitioners have mirrored many of the ideas from the book with tremendous and life-changing effects to our clients.

Aaron Grossman, MD

Founder and President of, Leading Expert in Health Optimization.

With The TOT Bible, Jay Campbell has created an avenue for all men to begin to enjoy a more healthy and fulfilling life. Medicine today is literally incapable of producing a reference text with the information Jay has compiled. He seeks the truth through science and real life clinical data/experience. Traditional medicine is a victim of its own system, and it takes true compassionate practitioners like Jay to convey the message of testosterone's crucial role in optimizing men's health. Anyone interested in maximizing his healthspan needs to read this book. His message is strong and clear. The real world guidance he provides is precisely what is needed to begin to "right your own ship" of health and wellness.

H. Merrill Matschke, MD
Board Certified Urologist and Fellowship
trained expert in Andrology/Men's Sexual Health & Wellness

What I REALLY like about my good friend Jay Campbell’s book is it covers ALL areas of men’s health; not just the Interventional Endocrinology, but also diet, supplementation, exercise, and the “anti’s”: anti-inflammation, anti-cancer and anti-heart disease. It’s truly a one stop shopping manual for the man who wants to optimize his health and happiness….from a guy who is the best living example of his own great advice!

John Crisler, D.O., Age Management Medicine

Founder of

The Testosterone Optimization Therapy Bible by Jay Campbell and Jim Brown is the most comprehensive, up to date, and insightful book on this exciting and very important topic. For men interested in health and longevity, combined with the willingness to take control of their destiny, this book is an absolute must read. The information herein is well written, easy to read, scientifically informative, and can be appreciated by non-physicians and physicians alike.

Christopher Foucher, MD

Clinical Associate Professor at MSU-COM's
Anesthesiology Residency Program

Jay Campbell’s knowledge in testosterone optimization therapy is simply stunning. His books gave me such great and practical advice to use with my patients. The wisdom he shares is profound, offering a much better quality of life and increased longevity. I have recommended his book to every single Age Management Practicing Doctor I know in South America.

Vicente Coutinho, MD, VPC

Integrative Medicine Clinic, São Paulo Brazil

The Testosterone Optimization Therapy Bible, written by Jay Campbell and Jim Brown, should be read by any man who seeks to achieve optimal health. He brilliantly explains the benefits and risks of testosterone replacement therapy (TOT) in a way that is easy to understand, yet it has depth. I have noticed in my practice that the men who have read this book are extremely knowledgeable about TOT, and it actually makes my interaction much easier as they are already educated patients. I decided to read the book as a result of my patients raving about it. Though I am very experienced with prescribing TOT, I actually picked up many pearls from reading it. This book is a must read for patients as well as physicians!

Lynese Lawson, D.O.

Founder of Pro-Active Wellness Centers Vienna Virginia

The Testosterone Optimization Therapy Bible is the real deal. It gives the reader years of medical research, experience from the gym and a real world, yet scientific understanding of TOT, delivered in a format which will help anyone wanting to help themselves. Jay and Jim’s book is THE resource manual for professionals, strength trainers, athletes and anyone else wanting to utilize testosterone safely and in the context of long term health.

Leonard A. Farber, MD

Clinical Director of Radiation Oncology of Lower Manhattan
The Farber Center for Radiation Oncology

Jay Campbell, in The Testosterone Optimization Therapy Bible, has synthesized a vast body of evidence, as well as the extensive experience of countless doctors and other professionals, into a concise, understandable, and immediately applicable manual. Whether you are a man in need of direction in the much misaligned and misinformed arena of TOT, or a physician interested in doing a better job for your patients, this book is written precisely for you. Read it, reference it and put it into practice.

James D. Dickie, MD

Leader in Age Management Medicine and Hormone
Replacement. Founder of

Jay Campbell has been a visionary in men's health for nearly two decades. His passion and commitment to help people navigate the broken medical system comes shining through in his new must read book The TOT Bible: The Ultimate Guide to Living a Fully Optimized Life.

Russ Scala

Founder, The Institute of Nutritional Medicine
and Cardiovascular Research

If you're looking to obtain, and maintain, youth, strength and sexual vitality as you age, Jay Campbell is the man you need to listen to. The TOT Bible provides a clear cut blueprint on how to optimize hormone levels for health, performance and freedom from the ills of aging. Don't succumb to old age gracefully — fight it tooth and nail! This book will show you how.

Nelson Montana

Author-The Bodybuilding Truth, Writer for Muscle & Fitness,
Muscular Development, Iron Man and Testosterone Nation

The concept of “health” has become compartmentalized by the modern fitness and medical fields to be narrow definitions of exercises, diets, and normal range lab tests. Regarding hormonal health and the role of testosterone, there has been a dearth of quality information available, and millions of men operate today in total ignorance of how their own hormones are affecting their daily well being. What Jay has done with The Testosterone Optimization Therapy Bible is create an unparalleled, holistic resource that synthesizes the science, data, and real world evidence into a practical guide for all men everywhere to understand and take control of their health on all fronts. Any man with this guide is no longer in the dark about what optimal health means. The TOT Bible provides the tools to create that for himself.

Alexander Juan Antonio Cortes

Writer, Author, Top 10 Most Influential Fitness Writer

Inspiring is Jay's knowledge of hormone replacement and human physiology, which surpasses that of many of my medical colleagues. This he brings to you, the reader, in the pages of his much-needed and timely opus. Open your eyes, read and digest Jay's words. This book is the chapter that I was scared to write.

Brett Osborn, MD

Diplomate, American Board of Neurological Surgery Diplomate, American Academy of Anti-Aging Medicine CSCS, National Strength and Conditioning Association, Author of Get Serious, A Neurosurgeon's Guide To Optimal Health and Fitness

The Testosterone Optimization Therapy Bible presents practical information about the best ways to maximize benefits and minimize side effects of testosterone replacement therapy. It accomplishes this goal in the most visually appealing way I have ever seen in this field. This book is an enjoyable and highly empowering read for any man who wants to take charge of his health and quality of life.

Nelson Vergel, CEO and, Author of Testosterone: A Man’s Guide: Practical Tips For Boosting Physical, Mental and Sexual Vitality

If there’s one thing the health care debate has made clear, it’s that everyone is ultimately responsible for their own health and wellness. And for men today, that includes educating themselves on the growing epidemic of low testosterone. In The TOT Bible, Jay Campbell and Jim Brown break down the causes, symptoms, and available treatment modalities for low testosterone, and how to work with your physician to obtain the safest, most effective care available. This book is a must-read for every man who wants to live up to his full potential.

Bryan Krahn CSCS

National Strength and Conditioning Association, Writer for
Men’s Health, and

The TOT Bible by Jay Campbell and Jim Brown is an excellent source of information regarding the basics of hormonal optimization. The text is written in a very engaging yet simple form, allowing the beginner to understand the hormonal aspects of hypogonadism. I highly recommend it for any man who wishes to change his quality of life especially moving into middle age. I have to admit that my supervisor, who is a general pathologist, found it really informative.

George Touliatos, MD

Biopathology Specialist, expert on medical prevention regarding PEDs use in sports. Medical Contributor for Anabolics 11th edition (2017), Writer for, Musclemag & Muscular Development magazines.

Jay Campbell and Jim Brown's The TOT Bible: The Ultimate Guide to Living a Fully Optimized Life, delivers a punch to the face of hormonophobia governing modern societies around the globe. Critical aspects of male interventional endocrinology are broken down and explained in a simple, clear, enjoyable and highly educative manner. Jay Campbell's commitment, accompanied by his vast knowledge in the testosterone optimization therapy field, resulted in the creation of a helpful and applicable hormonal optimization tool for both patients and physicians. Every single man dreaming of an ultimate optimized everyday life should get their hands on this manual as quickly as possible. Aging has finally met its match.

Nick Sakkas, DVM, MD, PhD

Candidate in Molecular Endocrinology, School of Medicine,
University of Ioannina, Greece.

Jay Campbell's The TOT Bible: The Ultimate Guide to Living a Fully Optimized Life, is a must read for all physicians interested in optimizing the health of their male patients and for any patients looking to live a life full of vitality. This book serves as a guide for all men who desire to take responsibility for their own health, acquire the right knowledge to help them make the right decisions, and want to be cutting edge. Our modernized environment is sabotaging our hormone balances. A proactive approach to living an optimized life as outlined in the pages of this book serves as the ultimate resource for men.

Bob Harding, D.O.

Men's Integrative and Functional Medicine Physician, Austin, Texas

I have nothing but praise for Jay Campbell's book, The Testosterone Optimization Therapy Bible. As an Age Management Physician, I was quite impressed with the context, format and well referenced chapters. Without reservation, I feel this book is a must have for any physician or male patient interested in OPTIMAL healthy aging for lifespan quality as well as quantity in years.

Stephen M. Ellestad, D.O.

Table of Contents



Introduction: The Unapologetic Truth About Testosterone

Chapter Summaries

Chapter 1 - Why are Men Losing Their Masculinity In The 21st Century?

What this Book Is

What this Book is Not

Key Takeaways

Chapter 2 - Why Optimizing Your Blood Testosterone Levels Will Transform your Physique

Testosterone Decreases Body Fat

Testosterone Increases Muscle Mass

Testosterone Improves Heart Health

Testosterone and the Brain

Testosterone and Dopamine

Testosterone and Depression

Testosterone and Memory

Testosterone Combats Alzheimer’s Disease and Improves Cognition

Testosterone Prevents Osteoporosis and Frailty

Testosterone Fights Inflammation

Key Takeaways

Chapter 3 - The Power of Testosterone to Transform Your Life

Testosterone and the Manifestation of Will

Testosterone will Improve Your Sexual Confidence with Partners

More Testosterone Equals Heightened Sex Drive and Libido

The Competitive Edge Gained From Using Testosterone

Testosterone Helps You Take Risks And Achieve Higher Social Status

Optimal Testosterone Levels Lead to Your Most Powerful and Enlightened Self

Key Takeaways

Chapter 4 -The Natural Testosterone Boosting Myth

Tongkat Ali

Tribulus Terrestris

Zinc Magnesium Aspartate (ZMA)


D-Aspartic Acid

The Only Proven Way to Raise Testosterone

Raise Libido, Raise Testosterone?

Key Takeaways

Chapter 5 - Testosterone 101: Understanding the Biological Role of Testosterone

What is Testosterone and How is It Made?

Why Do Men Stop Producing Optimal Levels of Testosterone?

Endocrine Disruption from Modern Day Societal Living

Defining Hypogonadism

Key Takeaways

Chapter 6 - Choosing When to Optimize Your Testosterone Levels

Is There an Ethical Dilemma in Choosing to Use Testosterone?

Testosterone Levels Decline with Age

Symptoms of Low Testosterone

ADAM (Androgen Deficiency in Aging Males) & AMS (Aging Males Symptoms)

Know Your Testosterone Levels, Understand Your Test Results

The Normal Range Fallacy

Vital Life Markers Necessary for TOT

How to Get Tested for Low Testosterone

Key Takeaways

Chapter 7 - Testosterone Optimization Therapy - Non Injectable Options

Bio-identical Testosterone

Creams and Gels

Natesto Nasal Gel

Oral Forms of Testosterone

Buccal Preparations

Testosterone Pellets


Key Takeaways

Chapter 8 - The Optimal TOT Protocol: Injectable Testosterone

Testosterone Undecanoate

Testosterone Propionate

Testosterone Cypionate and Testosterone Enanthate

Our Recommended TOT Protocols

The FDA and Testosterone Therapy

Choosing the Right TOT-Prescribing Physician

Vetting Your TOT Doctor

The Costs of TOT

Key Takeaways

Chapter 9 - How To Properly and Safely Inject Yourself for Life

Syringe, Needle Gauge, and Withdrawing

Where To Inject The Needle, and How to Inject Yourself Safely

TOT Via Subcutaneous Administration

Needle Disposal

Minimizing Scar Tissue Formation with Foam Rolling and Myofascial Release

Key Takeaways

Chapter 10 - Potential Side Effects, Their Likelihood, and How to Alleviate Them

Estradiol (E2)


Baldness and Acne


SERM’s (Selective Estrogen Receptor Modulators) and AIs (Aromatase Inhibitors) to Treat Side Effects

The Usage of AIs and SERM’s as TOT

Metabolic Syndrome, Obesity, Insulin Resistance, Aromatase and Estrogen

Key Takeaways

Chapter 11 - Eliminating Gynecomastia Permanently

Types of Gynecomastia

Option 1 - Conceal/Avoid

Option 2 - Lose Fat, Build Muscle, & Balance Hormones through TOT

Option 3 - Surgical Removal

Key Takeaways

Chapter 12 - Monitoring TOT for Optimum Health

Understanding Your Blood Panels

BioMarker Cheat Sheet

Evaluating Blood Testosterone

The Importance of Sex Hormone Binding Globulin (SHBG)

Hematocrit and Hemoglobin

Liver Health

PSA (Prostate-Specific Antigen) & Prostate Health

Blood Pressure

Sleep Apnea and TOT

Heart and Vascular Health

Lipids (Blood Fats) and Cholesterol Health


Testicular Shrinkage, Low Sperm Count and HPTA/HPGA Dysfunction

The Myth of Penis Shrinking

Why Cycling Testosterone is a Myth

Key Takeaways

Chapter 13 - The Critical Role of Nutrition in TOT

Your Caloric Intake is Dependent on Your Physical Goals

The Specific Macronutrients Needed on Your TOT Nutrition Plan

Vitamin & Mineral Supplementation to Maximize TOT

What to Minimize and Avoid While on TOT

Proper Hydration - How Much Water is Enough?

The Importance of Vitamin D from Sunlight and Supplementation

Key Takeaways

Chapter 14 - What is Insulin-Controlled Living, and Why Is it Essential?

How Insulin Works

Insulin and Glucose Utilization

Insulin Resistance

Major Myth of “Insulin Hypothesis”

How Do You Manage Your Insulin?

Good Carbs vs Bad Carbs

Optimal Versus Suboptimal Carbohydrate Consumption

Overall Plan of Attack

Key Takeaways

Chapter 15 - Agents of Change





Citrulline Malate


Desiccated Thyroid

Energy Memory Focus (EMF) (OTC Nootropic)

Human Growth Hormone (HGH)


Ipamorelin for Women

Melanotan I and Melanotan II





Thymosin Beta-4

Future Agents of Change

Key Takeaways

Chapter 16 - TOT and Fitness

The Foundational Role of Weight Training

Building Muscle and Strength

The Cardio Equation - How Much and What Kind?

The Importance of Sleep

Dealing with Injuries

Spiritual Fitness

Key Takeaways

Bonus Chapter 17 -The State of the Science in Male Hormonal Optimization: Interview with Dr. Rob Kominiarek

Key Takeaways

Bonus Chapter 18 - Hormonal Optimization Therapy (HOT) for Women: Doing it the Right Way

Female Health is Neglected

Hormone Deficiencies are a Disease at Any Age

Hormone Deficiencies are a Health Priority

Birth Control is NOT Hormone Restoration:

Pre- and Perimenopause

Key Principles in Female Hormone Optimization Therapy (HOT)

Applying the Key Principles

Key Takeaways

Bonus Chapter 19 - The Stone Cold Truth about Anabolic and Androgenic Steroids (AAS)

Don’t Ask About Steroids Until You Understand Steroids

A Brief Mention of AAS Drugs (Most Popular Synthetics)

Do Anabolic Steroids Work?

The Biological Differences Between Testosterone in Men and Women

Does TOT Count As Steroids?

Difference Between TOT and AAS

Potential Negative Side Effects

The Effects of AAS on Mood

What About the Increased Strength and Size?

How Much Expected Muscle Gain?

The Downside to Taking Steroids

Putting Pro Bodybuilding History Into Perspective

Key Takeaways

Bonus Chapter 20 - TOT and US Military Veterans: The Problem and Solution

Tales From the Blast Factory: A Veteran’s Story

Testosterone and the Road to Recovery

Looking After Our Veterans


Getting Treated

Out with the Old and In with the New

Key Takeaways

Chapter 21 - Conclusion

The Golden Rules

Frequently Asked Questions

TOT Resources

About the Authors

The Science Team

The Editing Team

A Sincere Request


(1) Introduction

This disclaimer governs the use of this book. [By using this book, you accept this disclaimer in full. / We will ask you to agree to this disclaimer before you can access the book.] No part of this book may be reproduced in any written, electronic, recording, or photocopying without written permission of the publisher or authors. All trademarks are the exclusive property of

(2) Credit

This disclaimer was created using an SEQ Legal template.

(3) No advice

The book contains information about Testosterone Optimization Therapy. The information is not advice, and should not be treated as such. You must not rely on the information in the book as an alternative to medical advice from an appropriately qualified professional. If you have any specific questions about any matter you should consult an appropriately qualified medical professional. If you think you may be suffering from any medical condition you should seek immediate medical attention. You should never delay seeking medical advice, disregard medical advice, or discontinue medical treatment because of information in this book

(4) No representations or warranties

To the maximum extent permitted by applicable law and subject to section 6 below, we exclude all representations, warranties, undertakings and guarantees relating to the book. Without prejudice to the generality of the foregoing paragraph, we do not represent, warrant, undertake or guarantee:

• that the information in the book is correct, accurate, complete or non-misleading;

• that the use of the guidance in the book will lead to any particular outcome or result;

(5) Limitations and exclusions of liability

The limitations and exclusions of liability set out in this section and elsewhere in this disclaimer: are subject to section 6 below; and govern all liabilities arising under the disclaimer or in relation to the book, including liabilities arising in contract, in tort (including negligence) and for breach of statutory duty. We will not be liable to you in respect of any losses arising out of any event or events beyond our reasonable control. We will not be liable to you in respect of any business losses, including without limitation loss of or damage to profits, income, revenue, use, production, anticipated savings, business, contracts, commercial opportunities or goodwill. We will not be liable to you in respect of any loss or corruption of any data, database or software. We will not be liable to you in respect of any special, indirect or consequential loss or damage.

(6) Exceptions

Nothing in this disclaimer shall: limit or exclude our liability for death or personal injury resulting from negligence; limit or exclude our liability for fraud or fraudulent misrepresentation; limit any of our liabilities in any way that is not permitted under applicable law; or exclude any of our liabilities that may not be excluded under applicable law.

(7) Severability

If a section of this disclaimer is determined by any court or other competent authority to be unlawful and/or unenforceable, the other sections of this disclaimer continue in effect.

If any unlawful and/or unenforceable section would be lawful or enforceable if part of it were deleted, that part will be deemed to be deleted, and the rest of the section will continue in effect.

(8) Law and jurisdiction

This disclaimer will be governed by and construed in accordance with law in the United States of America, and any disputes relating to this disclaimer will be subject to the exclusive jurisdiction of the courts of the United States of America. Testosterone is classified as a controlled substance under the Anabolic Steroids Control Act of 1990 and has been assigned to Schedule III. It is regulated by the Drug Enforcement Agency (DEA).The use of testosterone is illegal in the United States for those without a valid medical diagnosis and prescription justifying their use.

(9) Our details

In this disclaimer, "we" means (and "us" and "our" refer to) Jay Campbell (Southern California, USA) and Jim Brown (South Florida, USA) and or any future addresses, temporary or permanent.


This is the most challenging aspect of writing a book. Because there are so many people who have profoundly influenced our lives, it would be impossible to acknowledge and thank them all. But we have to start somewhere.

First, we could not have attempted to write this book, let alone finish it, without the help of the greatest things that ever happened to us—our wives—Monica Campbell and Rosie Brown. Their enormous self-sacrifice and encouragement compelled us to do and be more in every aspect of our lives, this book included. Through their example, we’ve both learned the greatest form of acceptance—unyielding and unwavering love and gratitude.

Second, heartfelt praise and gratitude to Joshua Smith, our business partner and mentor whose internet marketing mastery is allowing us to change the face of the sports supplement and hormonal optimization industries.

To doctors Jim Meehan, John Crisler, Merrill Matschke, Rob Kominiarek, Aaron Grossman, Brett Osborn and Joseph Cruise, whose visions are creating a personalized health care revolution. To Nelson Vergel for being the original torchbearer and passionate men’s health advocate. To Natalie Minh for her uncanny wisdom and creative insights into the Fitness space. To Binais Begovic for providing us the global platform to extend our knowledge. To Matt Lawrence for his design skill and website architecture expertise. To Humbert Glaffo for his amazing cover artwork.

To all our families, friends and social media and forum brothers, ex-wives, girlfriends, clients, and fitness industry peers, thank you for the assistance and intel you provided in our times together while researching this material for more than 25 years.

Last but not least, thanks to our editing team and dear friends Tom Zakharov, Alexander Cortes, Daniel Kelly, Michael Kocsis and Austin Gunter for their editorial oversight and help turning this book into the bible of total life optimization.

This book is dedicated to Lee Myer, the amazing and devoted husband and father who also founded

Lee was killed in a tragic car accident while picking up his children from school in January of 2018. He was a man who toiled in the shadows for years when Therapeutic Testosterone was not accepted in the public eye. His website was responsible for educating millions of of men unable to get proper care and treatment from the Medical profession. Much of his research and work guided me in writing both of my books.

I only wish I could have met him in person. Both Jim and I are humbly indebted to him for his sharp wit and excellent evidence based research. May he rest in peace.


I’m incredibly honored to have the opportunity to write the foreword for this amazing book! My good friends Jay Campbell and Jim Brown, along with the content inside this book, have completely changed my life. I would like to share my story about how all of it happened.

In my early 20s, I lost my health. As a teenager, I was in good shape and working out was a large part of my life. Then, in my early 20s, I became seriously depressed and stopped taking care of my health. Before I knew it, I had gained over 100 pounds of pure fat and was morbidly obese. After a couple years of going down this path, I decided that it wasn’t for me. I made a firm commitment to my health and lost the weight through hard work and patience.

Despite successfully losing 118 pounds, I wasn’t doing any physical activity. At that point, I was what Jay refers to as “skinny fat.” I was skinny with very little muscle and moderately high levels of body fat. That’s not the outcome I wanted, so I decided to turn that around by working out with weights and eating an extremely clean diet. During this process, I started realizing how much internal damage I had done to my body from being morbidly obese and consuming so much junk food.

Fast forward to 2015, where I am now 33 years old. I am working out with weights 5 times per week, doing cardio at least 4 times per week and I am eating extremely clean. When I say that I was eating extremely clean, I am talking about eating nothing but “organic” foods, juicing greens and taking all the right supplements. According to my family doctor, I was in absolutely amazing health. All’s well that ends well, right?

Not quite, because there was still one major issue: My energy levels were HORRIBLE. How could someone at 33 years old be in ‘absolutely amazing health’ but still feel awful at the same time? For the life of me, I could not figure out why I had low energy, low sex drive and high levels of brain fog. I thought it was because I was an entrepreneur who ran several busy companies at once, while taking care of 3 young kids at home. As much as I tried to accept this condition, there was still a burning feeling inside of me that said “This is not right, I should have more energy and feel better.”

I refused to accept that my low energy levels were due to old age, or my current stage of life. Luckily, that’s when I was first introduced to Jay Campbell. We were initially introduced by a mutual friend and had scheduled a 15-minute call to talk. That 15-minute call quickly turned into a 3-hour conversation that ultimately changed the course of my life.

Jay told me that all the symptoms I was experiencing were because of low testosterone levels. To be completely honest, I didn’t want to believe him. Being a grown adult man, I immediately correlated low testosterone levels with poor performance in the bedroom. Of course, like most men, I thought “Nope, I’m good in that department.” And having adopted such an “organic lifestyle,” I refused to put “chemicals” into my body.

Fortunately, Jay and I quickly developed a close friendship, probably because we are both entrepreneurs and have a lot in common. Every day, I thank God that he did not give up on convincing me to get my blood work done and my testosterone levels checked.

Several months later, I finally got to that level of frustration that most of us get to when we’re ready to make a change in our lives. I called up Jay, asked him where I should go to get my testosterone levels checked, and followed his instructions. One week later, I got my blood work back and I was SHOCKED! My testosterone levels weren’t just low: At the ripe age of 33, I had the testosterone levels of a healthy 80-year-old man!

I couldn’t believe it! Getting those test results back was a harsh yet eye-opening experience for me. With this realization in hand, I was finally ready to listen and apply everything Jay had been telling me for months.

I began working with a progressive physician and was prescribed something called “Testosterone Optimization Therapy.” Within 2 weeks, I felt like an entirely new man. I had massive amounts of energy, insane amounts of mental clarity, and zero brain fog. My sex drive was back, and I found myself sexually desiring my wife again! Not only that, but my performance in the gym also skyrocketed and I was CRUSHING all of my workouts!

Before following the protocols described in this book, I was only having sex a couple of times a month. I just chalked it up to being an extremely busy entrepreneur, having 3 young kids at home. I would never have imagined it was due to low testosterone levels.

Looking back on all this, it makes me wonder how many marriages are needlessly wrecked due to men having low testosterone levels. They still find their wives to be attractive, but they just don’t “want” her in the way that they used to. Sadly, the wives end up finding the attention they desire somewhere else. I was extremely fortunate to discover this issue and fix it before it became a real deal-breaking problem inside my own marriage. If you are reading this book now, you owe it to yourself and your wife to avoid becoming yet another broken marriage statistic.

Fast-forward a few months from this discovery, and Jay introduces me to his mentor Jim Brown. Hands down, Jim is one of the most brilliant individuals I have ever met! I have never met anyone that has his insane amount of knowledge about the human body, how it works and how to live a truly optimized lifestyle. In addition to everything I had learned and adopted from Jay, I started adopting the workout protocols, nutrition plans and supplementation protocols that Jim was teaching me. So far, the results have been nothing short of life-changing!

By following the protocols that Jay and Jim discuss in this book, along with the “Metabolic Blowtorch Diet” (their Amazon best-seller on optimizing intermittent fasting, get your FREE COPY at, I can honestly say that every aspect of my life has improved. I am a much better husband, father and entrepreneur than I ever thought was possible. My energy, my focus, the way I feel and the way I look - all of these things continue to improve on a daily basis.

At the end of the day, it is entirely up to each and every one of us to become proactive and take our health into our own hands. The government isn’t going to do it for you, and neither will your family doctor. The simple fact is this: NOBODY is going to do it for you. It is up to you to take full ownership of your health and live what Jay and Jim refer to as a “fully optimized life.”

Personally, I don't want to go through my life with ‘good’ health. I want to have EXCEPTIONAL health and have the energy and stamina to do the things I want to do, regardless of my age.

When you read this amazing book, I truly hope that you take the time to learn the information and apply it. I want you to understand it at a personal level so that you can take the MASSIVE action needed to transform your own life, ultimately giving you the life you truly want and deserve!

A personal note to the authors: Jay Campbell and Jim Brown, you have both had such a profound impact on my life that I can never personally thank you enough. Not just for changing my life, but for the amazing impact you have on so many others!

I truly appreciate and love you both!

Joshua Smith, CEO
Perfect Storm, Revisto Real Estate,
and Co-Owner of TRT Revolution LLC and
Optimized Life Nutrition


The Unapologetic Truth About Testosterone

We live in some interesting times for men. Our bodies are fragile and aging prematurely from the constant assault of urban environments, poor nutrition, and sedentary lifestyles, and this is causing many men to question their own masculinity. Is it any wonder our role in Western society is being questioned as well? These are not disconnected phenomena. Male health is faltering and too many men are living lives of quiet desperation, wishing for their weak bodies to become fit, wondering where their zest for life went, and abandoning any thought of ever getting it back.

But there is hope. The research has never been clearer, not only about how how male bodies are being destroyed by our modern environments and lifestyles, but ALSO how proven medical therapies can reverse the trend and return men to lives of vitality and contribution. In this book, we provide you with the scientifically proven method for optimizing the most important hormone in your body: Testosterone. And by the time you’re done reading, you’ll understand why optimizing your testosterone will transform your body, mind, and spirit.

Make no mistake, this book is about much more than undergoing testosterone therapy for purely physical or cosmetic reasons. We’re going to show you how to optimize your testosterone, and your entire life. Throughout this book, we will emphasize that testosterone therapy is a complete lifestyle, and is much more than simply taking a therapeutic dose of testosterone under your doctor’s care. Rather than simply viewing it as Testosterone Replacement Therapy, we invite you to make the shift and begin to see it as Testosterone Optimization Therapy (TOT).


Observant readers will note that much of the literature around testosterone therapy to date uses the term “Testosterone Replacement Therapy (TRT).” In this book, we put an end to that acronym for good. The idea of replacing “normal” testosterone levels in a world where the average man has suboptimal and consistently declining natural levels of testosterone makes no sense. This book goes far beyond merely replacing anything. This book is about optimizing testosterone levels in order for men to reach peak levels of health.

As a result, we will exclusively use the term Testosterone Optimization Therapy (TOT) throughout the book, and say with absolute confidence that if you use our book as a guide while working closely with the right physician, you will reach levels of health beyond anything you believed could be possible for you.

And whether you’re already convinced of the merits of TOT, or just starting to learn about the foundational role testosterone plays in your life, there is a single fact that bears repeating:

Testosterone is what makes men, MEN.

If you are one of the seekers who has already experienced the indisputable benefits of therapeutic testosterone, this book will educate you on the latest and most cutting-edge science behind TOT. We analyze and dissect the best testosterone optimization protocols so that you can make the most informed decision possible when working with a progressive physician and/or when designing your own customized testosterone therapy protocol.

Alternatively, you may be one of the millions of men whose natural testosterone levels have declined so dramatically that your zest for life no longer exists. Whether you’re in your 20s, your 30s, or even approaching "middle age," you wonder if you are destined to spend the rest of your life feeling lousy, tired, and lethargic. Deep down, you know you don’t have to, and that’s why you’ve picked up this book.

As you read the book, you’ll see how TOT is the paradigm-changing solution you need for living an exciting and purposeful life. And we should know: We have been living the pursuit of optimization for close to 30 years. We have tinkered, experimented, played human guinea pig, and bio-hacked our way to the physical and spiritual manifestation of OPTIMIZED MEN. Doing the work on ourselves has afforded us the opportunity to give back and help countless men around the world radically optimize and ultimately transform their lives.

In writing this book, we have 3 goals in mind to help men achieve this testosterone-fueled vision for themselves:

First, we want to stop men from being deceived by false claims from supplement companies selling ineffective testosterone booster supplements. We will demonstrate that there is no scientifically proven way to meaningfully raise your testosterone levels, other than through TOT.

Second, we want to offer the world THE definitive resource guide for all men seeking knowledge of legitimate testosterone products, testosterone optimization therapy, and everything that it entails. This book is your bible for truly living a testosterone-optimized lifestyle.

Finally, we want men to fully understand the greater sociopolitical climate and the controversy manufactured by the media to frame “testosterone” as taboo and polarizing. When men fully understand the false social narratives, it will become easier to fight the good fight and seize their natural potential.

Chapter Summaries

Here’s what we’ll cover, chapter-by-chapter, in this book.

Chapter 1 - Why Men are Losing Their Masculinity in the 21st Century shows you why so many men around the world have become emasculated, along with the importance of taking accountability for your health by working with a progressive physician.

Chapter 2 - Why Optimizing Your Blood Testosterone Levels Will Transform Your Physique is a deep dive into the physical benefits of optimizing your blood testosterone levels. You will discover how therapeutic testosterone serves to improve health in every system of the body.

Chapter 3 - The Power of Testosterone to Transform Your Life takes the previous chapter one step further by providing the intimate details on how optimal blood testosterone levels can literally transform every aspect of your life beyond the physical, from your personal affairs to growing your business.

Chapter 4 - The Natural Testosterone Boosting Myth shows you how to avoid falling for false promises of “all-natural” testosterone boosters, and clearly demonstrates how most supplements that claim to boost your testosterone levels are ineffective and a waste of money.

Chapter 5 - Testosterone 101: Understanding the Biological Role of Testosterone provides you a quick, concise and easy-to-understand breakdown of the biological role that testosterone plays in your body. Think of it as your “Endocrinology for Dummies” Cliff Notes guide.

Chapter 6 - Choosing When to Optimize Your Testosterone Levels is a pivotal chapter that teaches you how to recognize whether you may be suffering from suboptimal levels of testosterone. You will learn about the symptoms of low testosterone, the specific tests you must take to determine your symptoms, what really defines normal testosterone levels, and how to get tested properly.

Chapter 7 - Testosterone Optimization Therapy: Non Injectable Options will introduce you to the various non-injectable delivery systems for testosterone: creams, gels, nasal sprays, pellets, troches and patches. We cover them all and show you which ones are worthy solutions for lifelong TOT.

Chapter 8 - The Optimal TOT Protocol: Injectable Testosterone will teach you what has taken us nearly 20 years to learn: The OPTIMAL Testosterone Optimization Protocol. We go in-depth and analyze all the various injectable formulations of testosterone (Undecanoate, Propionate, Cypionate, Enanthate) and we also mention Sustanon for our European friends. We also discuss the importance of choosing the right doctor and the costs involved.

Chapter 9 - How to Properly and Safely Inject Yourself for Life covers everything you need to know about properly (and safely) injecting yourself with testosterone for life. We also discuss how and where to inject testosterone, the exact syringes to use, the correct needle gauge, and the optimal withdrawing procedures. You’ll quickly become a testosterone-injecting expert!

Chapter 10 - Potential Side Effects, Their Likelihood and How to Alleviate Them gets into the details of avoiding and minimizing the side effects of testosterone. This is a great chapter that teaches you EXACTLY how, when, and why you may encounter side effects. It also teaches you how to handle and effectively treat (if not eliminate altogether) side effects when administering testosterone.

Chapter 11 - Eliminating Gynecomastia Permanently offers much-needed help for the millions of men who suffer from gynecomastia and don’t know where to turn for an effective solution (If you think you might have ‘bitch tits’, this chapter is for you!).

Chapter 12 - Monitoring TOT for Optimum Health is not only for you, the patient, but for your doctor as well. We cut to the chase about monitoring your health, and taking regular labs and biomarker measurements as you age. This chapter is packed with research, studies, and citations that back up our recommendations on how to optimize your health for lifelong TOT administration.

Chapter 13 - The Critical Role of Nutrition in TOT examines the role nutrition plays in helping you get the most out of TOT. We break down the three major macronutrients (Protein, Carbs, and Fats) and discuss how supplements and specific vitamins & nutrients affect TOT. Additionally, you’ll hear our very strong opinions on alcohol, soy proteins, and sugar/High Fructose Corn Syrup.

Chapter 14 - What is Insulin Controlled Living and Why Is it Essential? is a layered and supremely important analysis of Insulin Controlled Living (ICL), and why you must embrace it to maximize TOT. There are very few books written in existence that discuss this complex topic in an easy-to-understand way, and/or offer actionable advice you can apply immediately. We do both.

Chapter 15 - Agents of Change is a chapter many of you will want to read right away. It contains the synthesis of Jim and Jay’s 30 years of biohacking efforts and being their own guinea pigs to discover the substances that optimize performance and alter the human physique. This chapter contains our very best recommendations, and gives you the foundation for biohacking yourself into a fully optimized life.

Chapter 16 - TOT and Fitness is a deep dive into the optimal ways to build muscle and lose fat through highly specific resistance and cardiovascular training protocols. You’ll also find out more about the often underestimated and undervalued role of sleep. And in maybe the most unique section of the entire book, you’ll learn why embracing the power of the now (i.e. spiritual fitness) might be the key to unlocking an entirely new and upgraded you.

Chapter 17 - The State of the Science in Male Hormonal Optimization: An Exclusive Interview with Dr. Rob Kominiarek is a groundbreaking and highly revealing interview with Dr. Rob Kominiarek, who offers profound insights regarding hormonal optimization in males. Dr. Rob has been prescribing testosterone for 22 years in his thousands of patients while also using it on himself. There are very few physicians with his experiential knowledge and insights on TOT.

BONUS: Chapter 18 - Hormonal Optimization for Women: Doing It the Right Way is an eye opening yet practical summary from Dr. Jim Meehan and co-author Monica Campbell on hormonal optimization for women. It’s a perfect lead-in for their book coming out in 2018 titled Cracking the Fountain of Youth Code - The Complete Women’s Guide to Becoming Leaner, Sexier, and Empowered for Life. Women will definitely want to read this chapter!

BONUS: Chapter 19 - The Stone Cold Truth About Anabolic Steroids is an excellent, high-level summary from Alexander Juan Antonio Cortes about Anabolic Steroids and how they differ from the usage of therapeutic testosterone. This chapter gives the average reader a very good understanding of how these two things are fundamentally different, despite what we have been led to believe.

BONUS: Chapter 20 - TOT and US Military Veterans: The Problem and Solution is a concise, yet powerful summary of the terrible situation that U.S. military veterans find themselves in when coming back from active duty, and trying to get properly evaluated by the VA. You will hear about veteran and ex special forces soldier Andrew DeMar, along with Dr. Mark Gordon, both of whom founded the Warrior Angel Foundation to help members of the U.S. military diagnosed with TBI (Traumatic Brain Injury) and PTSD (Post Traumatic Stress Disorder).

Chapter 21 - Conclusion reminds you that TOT is always based on a clinical need. Above all else, it is the conscious choice of a man who wants a better way to combat the modern day societal assault on his endocrine system and ultimately his long-term health.

THE GOLDEN RULES OF TOT contains 20 of the most important insights revealed inside the pages of the book. Each provides the reader with life-changing concepts they will now be able to apply to their own optimization quest.

FAQ’s are the best questions Jim and Jay have collected from the last 3 years regarding the use of TOT for lifelong health and happiness. These questions cover both hormonal and life optimization from every conceivable angle and aspect.

TOT Resources contain the best of the best in podcasts, websites, and articles that we believe will further inform you as you seek to optimize your life.

Private Coaching/Success Stories let you hear from (and see) some of the men who’ve completely transformed their lives while working with Jim and Jay utilizing the strategies found inside this book.

About the Authors shows you how to find Jay and Jim online and understand their missions.

The Science Team provides the profiles of the amazing progressive physicians who contributed to the research and insights found inside the book. It also allows you to directly interface with each so that you may consider them as an option in your decision to optimize your health.

The Editing Team provides the profiles of the amazing men who have taken Jay and Jim’s clinical research and made it understandable by all men and women in an easy-to-read and engaging way.

A Sincere Request is a friendly reminder to share this book with family and friends who may desperately need it. More importantly, we ask you to leave us an honest review (preferably 5 stars) on Amazon so that we positively impact millions of lives.

Each chapter will end with Key Takeaways designed to summarize the information, and restate the important bullet points to remember. There’s a lot of research condensed into each chapter, so you can review the Key Takeaways to reinforce the most important information found within.

*NOTE* We’ll use the word optimize a lot in this book. Before we go any further, let’s take a brief moment to define what optimize and optimization means in the context of health. Optimization means improving all your health markers from every conceivable and measurable angle. It also means optimizing your mind and your spirit as well. The health of your body, mind, and spirit all go hand in hand, and this book will touch on each of them.


Why are Men Losing Their Masculinity In The 21st Century?

The truth about the connection between testosterone and optimal health is hard to find. Despite living in an era of scientific inquiry and skepticism, there is an incredible amount of confusion and misinformation about the most important hormone in the male body.

But the truth is simple. Without testosterone, you are not a man. It is the hormone responsible for normal growth and development of male sex characteristics. If you doubt the power contained within this hormone, take a look at transgender women who inject this drug to transition into men and become champion athletes.

Testosterone formulations first came into existence when steroid chemist Adolf Butenandt of Schering partially synthesized them from a cholesterol base in 19351. This work was done in collaboration with fellow chemist Leopold Ruzicka and the pair were awarded the Nobel Prize in Chemistry in 19392.

Testosterone and its derivatives quickly became the target of invention and application to both humans and animals, and ‘testosterone esters’ were finally developed during what can be called the “golden age” of testosterone chemistry (from 1950 to the mid-1960s)3. These newly developed chemical compounds were specifically designed to reduce the speed at which testosterone breaks down in the human body. Using testosterone esters allowed physicians to better study and effectively treat a variety of medical conditions, including hypogonadism, anemia, wasting diseases, burns, recovery from surgery and trauma, age-related frailty, and many others.

As you can see, testosterone does a lot more for your body than increase the size of your biceps. It’s essential for every part of what makes you happy, healthy, and wise.

Most professional bodybuilders, fitness competitors, pro athletes, celebrity actors, and political leaders who use testosterone are forced to conceal their use of it. They must pretend to be 100% natural in order maintain their squeaky-clean image, and because the U.S. government classifies non-prescription testosterone use as a felony crime.

The modern-day reality is this: Testosterone levels in men are dramatically decreasing, and have been for more than 20 years across the USA4. Lower concentrations of testosterone increase a man’s risk for age-related diseases, depression and infertility5. Look at the accompanying data proving the population wide decline in testosterone over the 80’s, 90’s and 2000’s. Extrapolating this trend into the current day position, this is clearly a burgeoning crisis that the current medical community is either ignoring or completely unaware of.

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*NOTE* We want to be clear on something: This book is not meant as a backhanded slight to the established medical community who otherwise attempt to offer help by prescribing a wide range of therapeutic testosterone protocols to their patients. Many are doing the best they can with the limited information and long-term studies available to them. One of the primary purposes of this book is to be a resource guide for both the patient and the doctor to maximize TOT.

It’s also of significant concern and worry that there is no standard ‘patient of care’ model for optimizing hormone levels for men or women. The medical schools in the USA are sadly lacking when it comes to teaching TOT as a practice. Many of the Urology and Endocrinology physicians are only familiar with the “theories” and “textbook science8” of managing male endocrine systems. Unfortunately, they don’t have real first-hand knowledge gained from experiential learning (and managing thousands of patients). This privilege is only attained and shared by a select few. As with most things in medicine, practice-based experience is essential to provide the most up to date and advanced understanding of TOT.

If you want to safely and effectively optimize your blood testosterone levels, it is extremely important to consult with a prescribing doctor with considerable practice-based experience. Unfortunately, while this eliminates a huge percentage of physicians9, the purpose of this book is to guide you to a physician who is successful in prescribing therapeutic testosterone, thereby allowing you to achieve optimal health.

What this Book Is

This book is the first of its kind to create a better resource guide for Testosterone-Optimizing Therapy (TOT) physicians and their patients. You heard that correctly! This book displaces the tired and worn-out acronym “T-R-T” (Testosterone Replacement Therapy), and replaces it with something more instructive and positively inspirational for any man seeking to level up in his life. It also offers the hard-earned wisdom and calculated advice of men who have optimized their testosterone for nearly two decades under the supervision of experienced and forward-thinking doctors. This advice is backed by scientific research, citations, and data to clearly separate the truths from widely held myths and misbeliefs.

This book also relies heavily on molecular biology, bio-chemistry, and endocrinology to explain how TOT works while demonstrating its proven benefits. At the same time, it is written for all men to easily understand. All the TOT misnomers and conventional beliefs held by so many men for decades will be debunked and dispelled. In short, this book offers scientific and practical information on TOT that no aging man should be without.

As the authors of the book, we are not owned by any corporation or person. We can, and WILL tell you the whole truth about testosterone. We hold nothing back and give you everything that you need to know in order to make an informed decision about your health and well-being.

What this Book is Not

This is not a book about how to use Anabolic Steroids. There have been plenty of authoritative books written by superb researchers and scientists about using anabolics10,11. This book is a resource written for men on how to use testosterone productively and holistically for life. There is a difference between testosterone use and testosterone abuse.

This book provides crystal-clear strategies designed to optimize physical and mental performance, while enjoying the life-changing benefits of TOT. This allows you to become happier, more driven, improve your relationships, and live an incredible life.


If you follow the advice and guidance in this book, and do so under the supervision of a medical doctor who understands Testosterone Optimization Therapy, you will see every area of your health improve. And your life will be transformed as well.

So, with that out of the way…

Are you ready to learn how Testosterone
Optimization Therapy can improve your life
in every way possible?


• Testosterone is essential for every conceivable aspect of a man’s physical and mental health.

• Testosterone levels in men are dramatically decreasing, and have been for more than 20 years across the world. Lower concentrations of testosterone increase your risk for age-related diseases, depression and infertility.

• If you want to safely and effectively optimize your blood testosterone levels, it is essential to consult with a prescribing doctor with practice based experience.

• The authors of this book offer scientific and practical information on TOT that no aging man should be without. We WILL tell you the whole truth about testosterone.

• This book is NOT about how to use Anabolic Steroids, as other books have been written on that subject. It is specifically about the life enhancing USE (not ABUSE) of therapeutic testosterone.


Why Optimizing Your Blood Testosterone Levels Will Transform Your Physique

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People often ask why they should consider having their testosterone levels measured at all. The ONLY answer worthy of the question is this:


There is some controversy regarding the key signs which indicate that a man would benefit from (or even require) testosterone supplementation. This is due to a lack of large-scale, long-term studies assessing the benefits and risks of TOT.

Despite few sanctioned studies, reports from hundreds of thousands of men and their doctors prescribing TOT indicate that it often produces a wide range of benefits. Testosterone usage is not yet widespread, but the number of patients with a testosterone prescription rose from 1.3 million people in 2010 to 2.3 million in 201312. More than 50% of testosterone prescriptions are written by primary care physicians13 for middle-aged and older men with age-related declines in testosterone14. And these numbers are not even reflective of the global male population using TOT without a doctor’s prescription! The best estimates of this population grouping suggests that roughly 6 million people15 (without a prescription) are using anabolic and/or androgenic steroids (including testosterone) every year.

According to the U.S. Census Bureau, approximately 15 million men suffer from testosterone deficiency, a condition in which significant decreases in testosterone levels take place16. Shockingly, very few of these men will seek treatment. ‘Male hypogonadism’, a recognized medical condition in which the human body does not produce enough testosterone, remains dangerously underdiagnosed by many doctors.

Hypogonadism is often underdiagnosed for the following reasons:

1. Men don’t report it to their doctors because they are embarrassed to report symptoms that are sexual in nature. Additionally, they are conditioned to accept that these symptoms are typical of ‘old age’ and are therefore unfixable.

2. Men will often present nonspecific symptoms such as lack of motivation, depression, listlessness, and so on. Rarely is low testosterone investigated as the potential source for these symptoms.

3. There isn’t a definitive biochemical test for hypogonadism, nor is there a standard ‘patient of care model’ for physicians to follow.

4. There is a distinct lack of physician awareness regarding the condition. Many doctors do not understand what blood tests to order, as well as how to effectively and correctly identify the symptoms of a testosterone deficiency.

5. The U.S. Food and Drug Administration clarified in 2015 that prescribing testosterone due to aging constitutes off-label use. This institutes fear and disinterest in inexperienced primary care doctors (which are the majority of prescribers).

6. Many newer primary care physicians abide by the Endocrine Society’s recommendation: male hypogonadism should only be diagnosed if total serum testosterone levels are low on at least two early morning blood draws. This prevents many men who are suffering from symptoms from getting accurately diagnosed.

A very recent study shows that up to 40% of all tested men are dealing with suboptimal levels of testosterone17, and are suffering from the effects. Anecdotally, many progressive physicians report a much higher number of patients suffering from suboptimal levels of testosterone. Dr. Merrill Matschke18, a board certified urologist in a large suburban practice in Chicago (interviewed in Chapter 12), observes that 90% of his patients show up with subclinical levels of testosterone. He specifically states he rarely sees men with total testosterone levels higher than 400 ng/dL in his office.

That’s all the bad news, so here’s the good news: There are an endless amount of benefits to optimizing your testosterone levels, many of which you have never heard of or even thought were possible. And when you head down the life-altering testosterone optimization pathway, you’ll experience those benefits far sooner than you think!

Testosterone Decreases Body Fat

Testosterone is essential to the regula-tion of insulin, glucose, and fat storage19. Managing your body’s insulin production is the key to reducing inflammation as one ages (we will discuss the role of insulin much more in Chapters 13 and 14). As testosterone levels plummet, so does your body’s ability to process insulin, glucose, and fat. Simply put, a decrease in testosterone levels is directly correlated with an increase in fat storage20.

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To make matters worse for obese men (25% body fat or higher), an increase in fat also lowers testosterone levels. The fatter you become, the lower your testosterone levels go. This vicious cycle is a huge contributor to the obesity pandemic sweeping the world. As of October 2017, the CDC in the United States is reporting that 4 out of 10 adults are obese21.

In obese males, there is increased aromatase activity (aromatase is the enzyme directly responsible for converting testosterone into estrogen), which results in decreased testosterone levels and elevated estrogen levels. However, obese and high body fat men alike can break this cycle by undergoing TOT due to testosterone being lipolytic22 (i.e. fat burning). Studies have also shown that one of the positive benefits of testosterone treatment is a decrease in abdominal adiposity (also known as fat storage)23. The relationship between testosterone, aromatase, and obesity will be discussed in far greater detail in Chapter 10.

Testosterone Increases Muscle Mass

As the most essential muscle building (i.e. anabolic) hormone, testosterone improves muscle protein synthesis and therefore leads to more muscle growth24. The testosterone molecule is the foundation of muscle, strength, and the source of what makes men powerful.

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What does that mean? It means that if you exercise with progressively heavier weights25 while using testosterone, you'll increase your overall strength and build a more muscular physique. Remember: Muscle mass is the single greatest deterrent to the diseases of aging. The more muscle you possess, the more metabolically active you are and the more calories you burn at rest (i.e. sitting at your desk).

All of this leads to a body you’ll be proud of when you look at yourself in the mirror, whether naked or clothed. Building muscle is also of critical importance to combat sarcopenia (age related muscle loss) due to its protective effects on your joints, tendons, ligaments and bones.

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It is important to understand that a clean diet26 and a sound resistance training program27 are absolutely necessary to maximize the potential benefits of TOT28. We discuss these in detail in Chapters 13 and 16, respectively.

Testosterone Improves Heart Health

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Until very recently, researchers have been divided on the topic of how testosterone affects heart health. Previously, researchers had claimed that high levels of testosterone were linked to heart disease, while more recent studies have found that low testosterone levels are responsible for an increased risk of heart ailments29,30. Ultimately, there is now an overwhelming amount of recently published data31 which shows that maintaining optimal testosterone levels can help prevent cardiovascular disease32.

“Help” is the key word here. The benefits that come with healthy testosterone levels (not testosterone alone) are what allow the heart to maintain its strength.

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The hysteria created by mainstream media about therapeutic testosterone causing an increased number of CVD (cardiovascular disease) events in otherwise normal and healthy men is unsupported33. There is little data or proof substantiating the national TV, newsprint, and internet ads you may have seen and/or heard from legal groups and attorneys around 2014-2016 when they claimed that TOT increases the risk of heart attacks, stroke, CVD, and so on.

Unsurprisingly, the foundational study34 that prompted this witch hunt for CVD risk came from a clinical trial called “Testosterone in Older Men” (TOM) which investigated the use of topical testosterone (a.k.a. transdermal, which is suboptimal and will be covered later in Chapter 7) in men over 65 with limited mobility. Put another way, this was a study done on men who could barely walk or move on their own35.

I mean c’mon. How can any reasonable person assume that this study isn’t completely flawed due to the physical limitations of the subjects involved? And to think it was this tragically flawed study data a recent jury (October 2017) used to award a $140 million dollar settlement to a plaintiff who sued AbbVie, the maker of Androgel36. A plaintiff who turned out to be morbidly obese with high blood pressure, no less. Talk about an ironically hidden agenda!

*NOTE* Thankfully, a U.S. Court of Appeals Judge overturned this ruling on Dec 22nd 2017 and ordered a new trial set for March 5th, 201837.

Even with all of that, the preponderance of evidence clearly indicates an increased risk of cardiovascular disease and death in men with low or low-normal testosterone blood levels38. Therapeutic testosterone, when dosed and maintained to optimal levels, offers no increased risk of CVD and in recent studies39 offers clear protection from CVD. We offer much more information (including the latest research) about testosterone and its effect on the heart and vascular networks later in Chapter 12. Hint: it is supremely positive.

Testosterone and the Brain

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Testosterone exerts important biological effects on brain development and function throughout male life. Testosterone modulates the response of the amygdala (a key brain structure for generating and processing emotions) and the prefrontal cortex (a region of the brain involved in regulating emotional responses and reactions). Studies indicate that higher testosterone levels are associated with higher risk-taking, potentially leading to greater reward in both business and life40.

Testosterone and Dopamine

Testosterone's most noticeable effect on the brain is its ability to boost dopamine. Dopamine is a neurotransmitter (chemical messenger) that is responsible for transmitting signals between the nerve cells (neurons) of the brain. Dopamine is normally released when something good or exciting happens. According to this specific study, ‘testosterone can enhance dopamine release in the mesolimbic system, which may protect against depression and the associated decrease in dopamine activity in reward-related brain pathways’41. The brain is heavily dependent on testosterone to boost dopamine, as it’s one of the keys for a robust sex life. Many men feel the effects of increased dopamine (ridding of depression, more positive outlook, more energetic, etc.) immediately after beginning a TOT regimen.

Testosterone and Depression

One of global societies’ biggest health problems is depression. This afflicts hundreds of millions of men worldwide every year. Many scientists are stuck trying to figure out a biological riddle akin to the “chicken vs. the egg”: does low testosterone cause depression, or does depression cause low testosterone?

Sadly, the standard treatment (even to this day) is to prescribe selective serotonin reuptake inhibitor (SSRI) medications in lieu of submitting for a blood testosterone test. Despite this confusion, research now demonstrates that men undergoing TOT for suboptimal levels of testosterone report improvements in mood and other issues related to depression42. In fact, there are many studies showing that it dramatically improves depression and mood43.

Another study found that TOT may have an antidepressant effect in depressed patients, especially those with hypogonadism44. What is remarkable is that this study was willing to go on record and state that "the route by which TT [testosterone] is administered may play a role in treatment response." In other words, they actually admitted that testosterone can have a place in proper treatment of depression (in men with low testosterone levels).

Testosterone and Memory

Many studies have shown that testosterone improves working memory in men45. Working memory is the basis for nearly everything needed for proper brain function. Almost all processed information goes through working memory before it is analyzed, stored or synthesized by other parts of the brain.

Further studies have shown that visual and verbal memory improve in men who are given testosterone46. Even your ability to think is profoundly affected by testosterone! If that’s not enough, additional studies have shown that testosterone increases spatial processing power in both young and older men47.

In fact, the brain fog exhibited by men suffering from testosterone deficiency (also known by the clinical diagnosis acronym TD, which stands for Testosterone Deficiency) is often eliminated when men start TOT. The fastest and most noticeable positive effects of TOT are clearer thinking and an improved mood. As you can see, TOT’s ability to improve memory and increase cognition is quite possibly its most pronounced effect.

Testosterone Combats Alzheimer’s Disease and Improves Cognition

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Studies show that many older men with mild cognitive issues suffer from low blood levels of testosterone48. Many of these men eventually develop Alzheimer’s49. At the University of Southern California, researchers noted that increasing testosterone levels in older men stalled the development of Alzheimer’s50. This has led scientists to speculate that maintaining healthy testosterone levels may actually prevent Alzheimer’s51. There is also clear and substantial evidence to demonstrate TOT’s ability to improve memory (both long-term and short-term) in men as they age52.

Long story short: If you are an aging man and are interested in preserving your memory well into your golden years, make sure that your testosterone levels are optimized. It is one of the best preventative measures you will ever take for your mental and physical health.

Testosterone Prevents Osteoporosis and Frailty

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In multiple studies involving aging men, low testosterone levels are associated with lower skeletal muscle mass, muscle strength, physical function, bone mineral density and higher risk of fractures and death53. Low testosterone levels clearly cause bone disease in men, as testosterone is indisputably linked to bone health54.

Optimized blood testosterone levels increase bone density and impede the normal bone resorption issues that come with age (i.e. breakdown and destruction of bone tissue)55. Men who suffer from bone disease usually have suboptimal levels of testosterone, and this leads to frailty in old age56. The last thing any man wants is to end up with a deteriorated hip or spine that completely limits their range of motion later in life. No man wants to be a shadow of his former glory, stuck in a rocking chair and unable to move.

If you want ideal bone health into your later years, you owe it to yourself to optimize your testosterone levels.

Testosterone Fights Inflammation

Cellular inflammation is the core component of many aging-related diseases. It is the chief culprit of vascular disease, erectile dysfunction, autoimmune disease, and cancer57. Low levels of testosterone have been associated with a number of chronic inflammatory diseases, including an increase in cardiovascular disease markers58, mortality59, diabetes60, metabolic syndrome61, and an increased risk for bone fracture (i.e. the bone breaking). One of the primary ways testosterone improves biological systems is by decreasing inflammation.

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Excessive inflammation affects Leydig cell (located in the testicles) function and suppresses testosterone production. There is evidence from experimental studies that IL-6, TNF-alpha and IL-1 beta (the primary cytokines and major inflammatory markers) inhibit testosterone production by their suppressive influence on the Hypothalamus-Pituitary-Testes-Axis (HPTA)62. In plain English, IL-6, TNF-alpha and IL-1 beta control the levels of inflammation in the human body.

Studies have conclusively shown that suboptimal levels of testosterone lead to increased inflammation throughout the body. As such, we think it makes a lot of sense to briefly discuss the major inflammatory markers and how TOT has specifically been shown to improve each and every one of them.

Adiponectin is not an inflammatory cytokine per se, but it affects inflammation as it’s a chief culprit of decreasing insulin sensitivity (we discuss insulin sensitivity in much greater detail in Chapter 14). As men age, usually due to poor diet, fat gain and lack of exercise, adiponectin levels drop. TOT, on the other hand, raises adiponectin levels63.

As for the primary inflammatory cytokine IL-1, it is found in a number of conditions (such as rheumatoid arthritis). Researchers have proven that TOT inhibits IL-1 production64. TNF alpha is the primary cause of cardiovascular disease, and TOT has been found to lower TNF-alpha levels65. IL-6 is found in diabetes, cancer, and Alzheimer's. Guess what? Studies show that TOT decreases IL-6 levels66!

CRP (C-Reactive Protein) is now a common test given by progressive doctors to measure systemic inflammation levels. High readings are extremely well correlated to increased risk for heart disease, Alzheimer's, and Fatty Liver Disease (discussed in much greater detail later in Chapter 12). Testosterone deficiency has been found to be associated with higher CRP levels from insulin resistance, Type 2 diabetes, metabolic syndrome and vascular disease67.

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CRP values are easily affected by variable lifestyle changes such as colds, sinus infections, heavy and or intense physical training. Understanding this, it’s important for physicians to take this into consideration when evaluating CRP lab measurement numbers. It is also recommended Doctors test specifically for hs-CRP (high sensitivity-C-Reactive Protein) for a more accurate analysis of cardiovascular disease risk.

Although there has not been enough research regarding the link between testosterone and inflammation, the studies listed above provide conclusive evidence that testosterone suppresses pro-inflammatory cytokines (‘bad’ cytokines) and stimulates anti-inflammatory cytokines68 (‘good’ cytokines). Testosterone also seems to have a protective effect on beta cells (which make insulin) through its suppression and control of these inflammatory cytokines. In Chapter 20, you’ll see an example of the powerful anti-inflammatory effect of testosterone and how it was used to heal a wounded Veteran.


• Therapeutic dosages of testosterone will completely change your physique via decreasing body fat and increasing muscle mass, but ONLY when living a dialed-in lifestyle consisting of a clean diet and productive resistance and cardiovascular training.

• TOT improves heart health while simultaneously preventing cardiovascular disease. The hysteria created by mainstream media about therapeutic testosterone increasing the risk of cardiovascular disease in otherwise normal and healthy men is scientifically unsupported.

• TOT exerts powerful biological effects on brain development and brain function by increasing dopamine, alleviating depression, improving cognition/memory and ultimately combating Alzheimer’s and dementia.

• TOT also prevents osteoporosis and frailty in aging men and women (which are usually the number 1 causes of death for the elderly).

• Finally, TOT has a profound effect on fighting inflammation via suppression of inflammatory cytokines and stimulation of anti-inflammatory cytokines.


The Power of Testosterone to Transform Your Life

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The physiological effects of optimized testosterone levels will transform men into healthier, happier, and incredibly productive human beings. However, the psychological effects will also change how you think and feel as a man. Your mindset, your will and your sense of self will change for the better as you optimize your blood testosterone levels and overall lifestyle.

Testosterone and the Manifestation of Will

Most men today do not realize the power that testosterone has to improve overall well-being, or how suboptimal levels of testosterone can prevent them from living fulfilled lives. And while we’ll cover the many health benefits of optimized testosterone levels, the link between life fulfillment and testosterone usually gets ignored.

This sounds too good to be true, but men who have optimized testosterone levels report having a dramatically improved outlook on life and a supreme confidence that they can take control of their destiny in a way they didn’t comprehend prior to using TOT.

Testosterone will Improve Your Sexual Confidence with Partners

In the animal world, high testosterone levels have been linked to dominance in the battle for mates69. The same is true for human beings70.

Studies have shown that when two men were instructed to fight for the affection of a woman, the man's aggression, ability to direct the interaction, and chances of attracting the women were positively associated with their testosterone levels (i.e. higher testosterone levels means more aggression, greater ability & higher chances of success) before the task71. There is truth to the idea that boldness is a powerful key to attracting potential mates, and there is little doubt that testosterone is responsible for this boldness.

Improving your testosterone levels can improve your ability to approach women and build quick rapport. From a standpoint of evolutionary biology, women can sense higher testosterone levels in men and they enjoy communication with males who give off this aura of high testosterone (in other words, they are more attracted to them)72.

There is even research73 indicating that women can ‘smell’ higher testosterone levels and seek them out during various points of their menstrual cycle. If you know this and are currently struggling with approaching women, or dating in general, why would you not want to investigate the route of TOT as a potential solution?

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More Testosterone Equals Heightened Sex Drive and Libido

There's an entire industry devoted to correcting low libido and erectile dysfunction through the use of artificial chemicals. However, nothing beats out the natural and awesome power of optimized blood levels of testosterone.

Testosterone Optimization Therapy can significantly improve your sex drive while improving the quality AND quantity of erections74. Testosterone is undeniably the most powerful male sex hormone, and many male sexual issues can be reversed through a well-designed testosterone improvement regimen.

Unfortunately, many men who suffer from low testosterone are routinely scripted Viagra (and/or Cialis) and an anti-depressant (ex. an SSRI) when they tell a doctor about their lowered libido. These solutions are treating symptoms instead of addressing the underlying cause.

For this reason, it is critical that TOT-trained physicians learn how to decipher the difference between a patient who has a true lack of desire, and a patient who has a real-life inability to perform due to suboptimal levels of testosterone.

This will be stated numerous times throughout the book but it is worth mentioning this here:

Symptoms, and then blood panels - MUST be taken into account before dispensing erectile dysfunction and mood-altering medications to patients.

The Competitive Edge Gained From Using Testosterone

Testosterone is responsible for the masculine need for victory and challenge75. One study even shows that a man’s testosterone levels may predict whether he will persevere through defeat or give in when faced with adversity76. Testosterone tangibly speeds up reaction times, improves eyesight and physical endurance, and produces feelings of invulnerability77.

Think of the times in your life when you’ve experienced the “thrill of victory” as your favorite sports teams won a big game, whether you were watching or participating. It’s exhilarating!

The same is felt in the business world when you close a big sale or sign the paperwork on a huge deal. There is ample scientific evidence showing that testosterone levels in men increase exponentially for days after winning a game or achieving something of great significance78.

Now, imagine incorporating those feelings into your everyday life when using therapeutic testosterone, because that’s EXACTLY what it’s like. Aren’t you looking to get that competitive edge back into your life? Of course you are, and TOT can help you become a much more productive entrepreneur and/or business person.

Testosterone Helps You Take Risks And Achieve Higher Social Status

Testosterone has been linked to risk-taking and higher status in men. Men with high testosterone have higher social status and tend to be more risk-prone (i.e. take greater risks and take them more often) than their low testosterone, lower-status brethren79. Many people (including the authors of this book) believe that the ability to calculate and assume risk throughout one’s life is what separates the truly successful from those wishing for success.

Testosterone levels rise after every victory a person experiences80. This creates a positive feedback loop where a man with higher levels of testosterone may triumph over an opponent with greater skill but lower testosterone levels. Testosterone is your winning streak! A recent landmark study on testosterone in rugby players provided amazing insights on how experienced individuals with optimal testosterone levels are more tactical, rather than dominant:

“...Testosterone induces dominant behaviour among higher ranking individuals and obedience or submissiveness among lower ranking individuals. We found no main or interaction effects of game type on acquiescence, but did find a significant interaction between seniority and testosterone. Senior players acquiesced less if their testosterone was high rather than low, while junior players acquiesced more if their testosterone was high rather than low.

This interaction effect between testosterone and social status among persons embedded in hierarchical relationships is a novel finding, which suggests the interesting possibility that testosterone is implicated in behavior that could be characterised as tactical rather than dominant81.

Optimal Testosterone Levels Lead to Your Most Powerful and Enlightened Self

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When you have higher levels of testosterone, your ability to be supremely confident in your decisions and take decisive action increases exponentially. You are assertive and purposeful in everything you do and say. Your decisions empower you to behave in ways others find attractive. You are no longer a man of words, but a man of calculated and tactical action.

TOT will help a depressed man become more assertive, giving him character traits that invoke his latent assertive spirit. And for the already assertive men out there, TOT will make you even more focused, determined and a stronger leader amongst your peers.

Being hormonally optimized gives you the mindset and focus to achieve your big goals. The connection between what you can accomplish, and the state of your physical health, is something that most men ignore. But once you realize what you can accomplish when your body is healthy, you’ll never look back.

We believe that everyone has something to contribute to the world. Optimizing your testosterone levels will dump high octane fuel in your tank so you can serve and do more for your community, your friends and your loved ones. This summary quote from deceased US tennis player Arthur Ashe regarding testosterone and altruism is a perfect way to express the awe- inspiring potential of optimized testosterone levels:

“True heroism is remarkably sober, very undramatic. It is not the urge to surpass all at whatever cost, but the urge to serve others at whatever cost. And endogenous testosterone appears to be one important driving source of this type of prosociality in human males.”


• Optimizing your blood testosterone levels has the potential to radically transform your business and personal life. Specifically, the physiological effects of optimized testosterone levels make for healthier, happier, and more productive men.

• Optimal levels of testosterone will improve your outlook on life and give you absolute confidence that you can take control of your own destiny.

• TOT will improve your confidence amongst sexual partners and improve your ability to approach women and build quick rapport. It will also improve your performance in the bedroom (via enhanced libido, and better quality and quantity of erections).

• TOT will dramatically improve and strengthen your mindset, thereby allowing you to possess and maintain a competitive edge.

• TOT will provide a sense of invulnerability, which potentially leads to high rewards and a higher social status. One study even suggested that individuals with optimal testosterone levels are more tactical, rather than dominant.

• Optimized testosterone levels will allow you to become the best and strongest version of yourself. In particular, your ability to be supremely confident in your decisions and take decisive action increases exponentially. You are assertive and purposeful in everything you do and say. Your decisions empower you to behave in ways others find attractive.


The Natural Testosterone Boosting Myth

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In the past 25 years, you’ve been bombarded by marketing gimmicks and ‘sounds-too-good-to-be-true’ ad campaigns from every conceivable form of media trying to sell you the latest and greatest “testosterone booster” supplement.

If you’re reading this book, there’s a very good chance you’ve already fallen prey to these ads and invested your hard-earned money into one of those ‘‘natural testosterone boosters.” We’re here to tell you unequivocally that nearly every one of those so-called boosters is a total scam82. These products are nothing more than unproven snake oil sold to millions of unsuspecting men who believe and buy into the hype. Men (maybe like yourself) who would do anything to look and feel better. The only thing these supplements have ever done is emptied the bank accounts of those people who swallow the "magic pills."

The companies that sell these boosters claim you can naturally raise testosterone levels through the use of their carefully selected herbal supplements. They make false promises and say that you’ll notice a better sex drive, bigger muscles, or even a larger penis from taking these natural remedies. However, none of them actually deliver on their claims. These solutions are ripoffs and will not provide a meaningful increase in your testosterone levels.

So why do they stay in business despite being so ineffective? Well, there are several factors behind their popularity.

First, we live in an ‘instant gratification’ society that encourages people to seek immediate results without doing the actual work. Our modern culture bows at the altar of the overnight success and the quick fix. Why spend years painstakingly building a testosterone-optimized lifestyle on a foundation of diet, exercise, and sleep when you can just take an “all-natural” testosterone booster and get the same results?

Fitness gurus on YouTube will market testosterone boosters to impressionable young men who see their extreme muscularity and believe that they will achieve a similar physique in ”just 60 days” by using these boosters.

Testosterone deficiency is a real, global phenomenon afflicting a massive number of men and it will only continue to grow. This means that there’s a growing market of millions of men who are looking for help. But after decades of media misinformation about testosterone, while mislabelling the use of therapeutic testosterone as ‘anabolic steroids’ or ‘juicing’, many men are reluctant to undergo hormone optimization due to erroneous concerns over dangerous side effects. As a result, they look to slickly marketed natural remedies in the hopes of boosting their testosterone levels. And now, tons of fraudsters have spun up YouTube channels and portrayed themselves as experts in order to turn a profit.

So what’s the cold hard truth about testosterone boosters?

The truth is that there’s little to NO SCIENTIFIC EVIDENCE which supports the claims made by supplement companies about their testosterone boosters actually raising testosterone levels.

We’ll discuss the five most popular herbal supplements typically found in testosterone boosters, and we’ll show why using them to raise testosterone levels is a pointless endeavor that will fail every single time.

Tongkat Ali

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Eurycoma longifolia, also known as Tongkat Ali, is a herbal supplement that has gained popularity in biohacking circles for its supposed ability to boost testosterone levels. However, most of the studies done on the potential of Tongkat Ali to raise testosterone levels have been done on rat populations, and the results are inconclusive. In one of the few studies done on humans, researchers tested the effects of 200 mg of water-soluble Tongkat Ali per day on men with late-onset hypogonadism83.

After 5 weeks, the mean increase in serum testosterone levels in 76 men was the equivalent to 80 ng/dL. This increase in testosterone is insufficient to notice any significant benefits when measured using the total testosterone measurement scale provided by Labcorp. We will discuss total testosterone level measurements in depth in Chapter 6.

Tribulus Terrestris

Tribulus terrestris is a plant extract that serves as a key ingredient in many testosterone boosters. However, its benefits appear to be confined solely to an ability to enhance libido. There is virtually zero scientific evidence to correlate Tribulus terrestris with a measurable increase in testosterone.

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In a double blind study, 22 elite male rugby players took 450 mg of Tribulus terrestris daily versus a control group who took a placebo84. After 5 weeks, there were no noted differences in urinary testosterone levels and lean body mass between the groups, both of which would be important qualitative indicators of higher testosterone levels. A further study of Tribulus terrestris supplementation in 21 young men showed no increase in testosterone levels after 4 weeks85.

Zinc Magnesium Aspartate (ZMA)

Another popular supplement purported to increase testosterone is Zinc Magnesium Aspartate (ZMA). Indeed, there is sparse evidence to demonstrate ZMA’s ability to increase testosterone levels. However, both overtraining and zinc deficiency (not necessarily in conjunction) are associated with a reduction in testosterone. When zinc is supplemented in these scenarios, it appears to increase testosterone but only minimally (without any enhancement in training-associated performance).

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In the absence of overtraining and a zinc deficiency, zinc appears to have little effect on testosterone levels86,87. Similarly, in one double-blind study, magnesium was shown to have no statistically significant influence on testosterone levels88. And in another study, the effects of ZMA supplementation on anabolism markers (which indicate muscle growth) in 42 resistance-trained males (i.e. males who regularly lift weights) showed no increase in testosterone levels after 8 weeks89.


Fenugreek, a plant believed to have the ability to increase libido and testosterone, is also a mainstay in testosterone boosters.

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However, the literature differs on Fenugreek’s testosterone-raising capabilities. In one study of Fenugreek as an aromatase and 5 α-reductase inhibitor on hormone levels90, average increases of 6.75% were noted in serum testosterone over an 8-week period. This means a man with serum testosterone levels of 350 ng/dL would see an increase to 374 ng/dL. This tiny increase is not enough to notice any significant benefits to health and/or well-being. Furthermore, the study is suspect because it was funded by a company that manufactures a Fenugreek-based workout supplement.

In a study on resistance-trained males, Fenugreek was shown to have no effect on hormonal levels, especially not testosterone91. And a randomized placebo study on the effects of Fenugreek on libido involved 60 healthy males taking 600 mg of Fenugreek daily92. After 6 weeks, positive improvements were noted in the males’ libido, but there was no effect on serum (i.e. total) testosterone levels.

D-Aspartic Acid

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D-Aspartic acid is an amino acid that naturally occurs in the body and can be found in the adrenal gland, pituitary gland and testes93. Recently, D-Aspartic acid has gained popularity as a testosterone booster because of its purported involvement in the synthesis and release of testosterone in the body. Therefore, the premise is simple - supplement with D-Aspartic acid and you will be able to boost your testosterone levels!

However, upon review of the literature, a familiar story emerges. There are minimal human studies on the efficacy of D-Aspartic acid and the results are inconsistent. One study was done on healthy male volunteers between the ages of 27 and 38 to determine the effect of D-Aspartic acid on fertility94. A total of 23 subjects consumed 3.12 grams of D-Aspartic acid for 12 consecutive days. Luteinizing Hormone (LH) levels and serum testosterone levels increased from basal levels by 33% and 42% respectively. At first glance, these results appear promising. However, on further inspection we find several holes in this study. Indeed, no inclusion or exclusion criteria of the sample population were included, and the only detail provided about the participants was their age. Therefore, we cannot truly determine if specific lifestyle factors (e.g. physical activity, supplementation, etc.) had any effect on the study.

Another randomized, double-blind study observed the effect of 3 to 6 grams of D-Aspartic acid daily in resistance trained men. Twenty healthy resistance-trained men, ages 18-36, performed weight training 4 days a week and took either a 3g placebo, 3g D-Aspartic acid or 6g D-Aspartic acid daily95. It’s interesting to note the participants had to be able to bench press 100% of their body weight to be eligible for the study. After 28 days, no significant effect on strength, body mass or testosterone levels were seen. Furthermore, 6 daily grams of D-Aspartic acid ”significantly reduced” total testosterone and free testosterone levels.

The Only Proven Way to Raise Testosterone

Some studies on herbal supplements do demonstrate a small increase in testosterone levels. However, these increases are both temporary and miniscule, and they cannot always be attributed to the supplement alone.

At best, you could use Tongkat Ali and MAYBE increase your total testosterone from 250 ng/dL to 330 ng/dL - a 32% increase. The problem is that you would still be suffering from suboptimal levels of testosterone, according to the total testosterone measurement scale of LabCorp (These measurement numbers of total testosterone are discussed further in Chapters 6 and 12).

There’s no reason to choose that option when a clinical dose of therapeutic testosterone is scientifically proven to optimize your testosterone levels by improving both your total and free measurement lab numbers. TOT works to elevate and optimize your testosterone levels, plain and simple.

With a TOT prescription, you can take your total testosterone from 250 ng/dL to the top of the range at 1000 ng/dL - a 233% increase. And trust us when we say that the difference in the way you feel at those higher ranges is NIGHT AND DAY!

Regardless of what you think of the pharmaceutical industry, it is heavily regulated by the FDA, and companies must perform rigorous laboratory tests so they can back their claims with hard evidence. By comparison, the supplement industry in North America is UNREGULATED. This means the majority of supplement companies can make claims on their products without providing any proof. So not only do these boosters not raise your testosterone, you don’t actually know for sure if the ingredients used are genuine (i.e. do they actually work)96. Another point worth mentioning is that some of these so-called boosters might actually reduce your testosterone levels (as in the aforementioned study with the D-Aspartic acid)!

Raise Libido, Raise Testosterone?

Even though we’ve thoroughly debunked testosterone boosters, you may still think, ‘If it increases my libido, surely it increases testosterone?’ That’s correlation, but not causation (i.e. increasing libido does not directly cause an increase in testosterone levels). The one underlying theme uniting all these supplements IS their reputation to enhance libido, and in some cases they’ve been used for centuries as aphrodisiacs. But this doesn’t mean that they raise testosterone levels. Your libido is comprised of more than just the amount of testosterone in your blood!

Testosterone itself is a pervasive symbol of masculinity, associated with sex drive and virility. And low testosterone is linked to a lack of sex drive in men. This is precisely where supplement companies trick unsuspecting consumers: By enhancing one’s libido, testosterone boosters can make it appear as if they’ve also increased one’s testosterone levels!

However, increased libido doesn’t automatically mean you have meaningfully increased your testosterone levels. Research shows that testosterone is not always a decisive factor in libido, and indeed estrogen also plays a vital role in male sexual function. In one study, for example, men with testosterone deficiency received exogenous estradiol (i.e. estrogen delivered into the body from an outside source) and experienced an increase in libido97. So think twice about buying any alleged libido enhancers in the vain hope that they will also increase your testosterone levels.

Nonetheless, we’re not here to toss out all supplements as garbage - far from it. As we’ll see later in the book, there are some fantastic supplements available that can be extremely beneficial to your health. However, there is minimal to no credible scientific research that suggests any nutritional supplements can meaningfully increase and optimize your testosterone levels.

Now, there wouldn’t be such a market for testosterone boosters if millions of men weren’t aware that their levels were below normal. And as you’ve already been shown, testosterone levels have been declining for the past several decades98 and the high market demand for testosterone supplements means that men like you are waking up to this reality.

Which leads many men to ask the following question:

“Why is my testosterone so low in the first place,
and why isn’t there a natural solution?”

The next few chapters will dive deeper into the science behind testosterone and why powerful environmental factors are currently overshadowing most men’s efforts to naturally fix their own testosterone levels.

If you have low testosterone, does it mean TOT is your only alternative? Not necessarily - it’s not that cut and dry. As we’ve demonstrated in this chapter, most testosterone boosters are bunk but you will very likely get some mileage by modifying your lifestyle. There is one product, Mike Mahler’s Aggressive Strength Testosterone Booster99, that provides clinical studies asserting the effectiveness of the product’s individual ingredients in boosting your testosterone levels. For an excellent article on how to maximize natural testosterone production, take a look at Alexander Juan Antonio Cortes’ “50 Natural Ways To Increase Your Testosterone”100.

If you’re like most men, there’s a good chance that you will benefit from the lifestyle changes Alexander recommends, including a modest increase in your testosterone levels. However, the reality is that modern-day environmental living continues to pl